Mild aerobic oxidation of benzyl alcohols to benzaldehydes in water catalyzed by aqua-soluble multicopper(II) triethanolaminate compounds
✍ Scribed by Paweł J. Figiel; Alexander M. Kirillov; Yauhen Yu. Karabach; Maximilian N. Kopylovich; Armando J.L. Pombeiro
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 279 KB
- Volume
- 305
- Category
- Article
- ISSN
- 1381-1169
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✦ Synopsis
The aqua-soluble multinuclear copper(II) compounds [Cu 2 ( -H 2) (H 3 tea = triethanolamine, H 4 pma = pyromellitic acid) have been applied as efficient catalysts for the mild, selective and clean oxidation of benzyl alcohols to benzaldehydes, which proceeds in sole water as solvent at 50 • C, under atmospheric pressure of air (or O 2 ) as oxidant, and is mediated by TEMPO radical. Molar yields of benzaldehydes (based on alcohol) up to 99% have been achieved (with a high selectivity). Attractive features of these catalytic systems include the use of organic-solvent-free reaction medium, air or dioxygen as oxidant, and aqua-soluble copper catalysts that are readily available by self-assembly.