Migration of vascular smooth muscle cells is enhanced in cultures derived from spontaneously hypertensive rat
โ Scribed by Chien-Cheng Hsieh; Y.-T. Lau
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 532 KB
- Volume
- 435
- Category
- Article
- ISSN
- 0031-6768
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The characteristics and proliferation of aortic smooth muscle cells (SMC) from spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats were studied in culture. Smooth muscle cells were isolated from the tunica media of the thoracic aorta by an explant method. Immunofluorescenc
Elevated vascular (VSMC) and bladder smooth muscle (BSMC) NGF are associated with altered visceral innervation in the spontaneously hypertensive rat (SHR: hypertensive, behaviorally hyperactive) compared with control Wistar-Kyotos (WKYs). Stretch stimulates increased NGF production in BSMCs. To eluc