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Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17

✍ Scribed by Maretzky, Thorsten; Evers, Astrid; Zhou, Wenhui; Swendeman, Steven L.; Wong, Pui-Mun; Rafii, Shahin; Reiss, Karina; Blobel, Carl P.


Book ID
111869869
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
307 KB
Volume
2
Category
Article
ISSN
2041-1723

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We have previously shown that transforming growth factor-b1 (TGF-b1) enhances the epidermal growth factor-(EGF) and transforming growth factor-a (TGF-a)stimulated motility of rat hepatocytes in an extracellular matrix (ECM)-dependent fashion (Stolz and Michalopoulos, 1997, J. Cell. Physiol., 170:57-