The discriminatory power of a quantitative heterozygote test for Maple Syrup Urine Disease (MSUD) which we have been using is analyzed on the presumption that a single rare mutant allele is involved in MSUD. Bayes theorem then predicts that only a small portion of persons from the general population
✦ LIBER ✦
Midwives’ Approach to Genetic Diseases and Genetic Counseling in Denizli, Turkey
✍ Scribed by Ayşe Gaye Tomatır; Aysun Özşahin; Hülya Çetin Sorkun; Huriye Demirhan; Beyza Akdağ
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 149 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1059-7700
No coin nor oath required. For personal study only.
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A general method to obtain the exact point estimate and the measure of uncertainty of recurrence risks for genetic counseling is present. This method, which follows Bayesian estimation theory, can be applied without restrictions of sample size, class of risk function, or parameter dimension. As an i