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Midbrain raphe lesion in the newborn rat. I. Neurophysiological aspects of sleep

✍ Scribed by Joëlle Adrien; Sylvie Bourgoin; Michel Hamon


Book ID
118863534
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
1010 KB
Volume
127
Category
Article
ISSN
0006-8993

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Effect of midbrain raphe lesion on the a
✍ R. Samanin; D. Ghezzi; C. Mauron; L. Valzelli 📂 Article 📅 1973 🏛 Springer 🌐 English ⚖ 267 KB

The antinociceptive action of several analgesics was studied by two methods: the hot-plate and the tail compression tests. Lesions of the midbrain raphe, which produce a marked depletion of serotonin in the forebrain, antagonize the analgesic effect of morphine but not that of methadone, meperidine