𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Midbrain hyperechogenicity in idiopathic REM sleep behavior disorder

✍ Scribed by Heike Stockner; Alex Iranzo; Klaus Seppi; Mónica Serradell; Viola Gschliesser; Martin Sojer; Francesc Valldeoriola; José L. Molinuevo; Birgit Frauscher; Christof Schmidauer; Joan Santamaria; Birgit Högl; Eduardo Tolosa; Werner Poewe

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
74 KB
Volume
24
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Recent studies have reported an increased risk to develop Parkinson's disease (PD) in patients with idiopathic RBD (iRBD). Midbrain hyperechogenicity is a common transcranial sonography (TCS) finding in PD and has been suggested as a PD risk‐marker in nonparkinsonian subjects. The objective of this study is to assess midbrain echogenicity by TCS in patients with iRBD and compare the findings with the healthy controls. TCS was performed in 55 iRBD patients and in 165 age and sex‐matched controls. The area of echogenicity in the SN region in the iRBD group was significantly increased compared with the control group (P < 0.001). About 19 (37.3%) of patients with iRBD were found to have SN hyperechogenicity when compared with 16 (10.7%) of the controls (P < 0.001). This is the first case‐control study assessing midbrain echogenicity in a large iRBD cohort compared to age‐ and sex‐matched healthy individuals. The finding of an increased prevalence of hyperechogenicity in a subgroup of individuals with a priori increased risk for PD supports the potential role of hyperechogenicity as a risk marker for PD. The prospective follow‐up of this iRBD cohort is needed to establish if those with midbrain hyperechogenicity will go on to develop clinically defined PD or not. © 2009 Movement Disorder Society

📜 SIMILAR VOLUMES

Rhythmic movements in idiopathic REM sle
Rhythmic movements in idiopathic REM sleep behavior disorder
✍ Raffaele Manni; Michele Terzaghi 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 346 KB

## Abstract Reported are two cases of video‐PSG captured head‐rolling occurring, in the context of REM Sleep Behavior Disorder (RBD) episodes, in two patients affected with idiopathic RBD and without past personal or familiar history of Rhythmic Movement Disorder during sleep. It has been speculate

Cardiac autonomic dysfunction in idiopat
Cardiac autonomic dysfunction in idiopathic REM sleep behavior disorder
✍ Ronald B. Postuma; Paola A. Lanfranchi; Helene Blais; Jean-Francois Gagnon; Jacq 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB

## Abstract More than 50% of persons with idiopathic REM sleep behavior disorder (RBD) will develop Parkinson's disease or Lewy body dementia. Symptom screens and metaiodobenzylguanine (MIBG)‐scintigraphy suggest autonomic abnormalities in idiopathic RBD, but it is unclear whether autonomic abnorma

Polysomnographic diagnosis of idiopathic
Polysomnographic diagnosis of idiopathic REM sleep behavior disorder
✍ Jacques Montplaisir; Jean-Francois Gagnon; Maria Livia Fantini; Ronald B. Postum 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 306 KB

## Abstract The presence of either excessive tonic chin EMG activity during REM sleep, or excessive phasic submental or limb EMG twitching is required to diagnose REM sleep behavior disorder (RBD). The aim was to identify cut‐off values and to assess the sensitivity and specificity of these values

Idiopathic REM sleep behavior disorder i
Idiopathic REM sleep behavior disorder in the transition to degenerative disease
✍ Ronald B. Postuma; Jean-Francois Gagnon; Melanie Vendette; Jacques Y. Montplaisi 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 176 KB

## Abstract Idiopathic REM sleep behavior disorder (RBD) predicts Parkinson's disease (PD) and dementia. However, the nature of the disease that emerges from RBD has not been fully characterized. Since 2004, we have been conducting a prospective study of idiopathic RBD patients, providing an opport

Odor identification test as an indicator
Odor identification test as an indicator of idiopathic REM sleep behavior disorder
✍ Tomoyuki Miyamoto; Masayuki Miyamoto; Masaoki Iwanami; Keisuke Suzuki; Yuichi In 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 117 KB

## Abstract Reduction of olfactory function in idiopathic rapid‐eye‐movement (REM) sleep behavior disorder (iRBD) is of the same magnitude as that found in patients with Parkinson's disease (PD) and dementia with Lewy bodies (DLB). We assessed olfactory function using the Odor Stick Identification