Micturition-facilitating mechanism in benign prostatic hypertrophy: A theory

✍ Scribed by A. Cucchi

• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: English
• Weight: 382 KB
• Volume: 6
• Category: Article
• ISSN: 0733-2467
• DOI: 10.1002/nau.1930060605

✦ Synopsis

Forty males aged 46-82 years (mean, 65 years) with bladder outflow obbtruction due to benign prostatic hypertrophy were chosen among a group referred for prostatism. They were assessed by means of symptom analysis, rectal examination, intravenous urography and/or cystoscopy, and urodynamic testing (medium-fill water cystometry and pressure flow study). Only those patients were considered who had compensated bladders with no severe trabeculation. A significant correlation was found in this series between urethral resistance and opening time (r = -.41, P < .Ol), the best fit being a negative exponential relationship (the higher the degrce of obstruction, the lesser the time needed to reach the threshold pressure at which flow begins). This was supposed to describe a real micturitionfacilitating mechanism, which might be explained by abnormal activation of a nerve pathway relaying through the spinal cord between the proximal urethra and detrusor muscle. Such a mechanism would be valid for those proximally obstructed bladders with mild to moderate detrusor collagenosis.