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Microwave-assisted synthesis of phenylenedi(4′,4“-tetrahydroquinoline) and di(4′,4”-tetrahydropyridine) derivatives

✍ Scribed by Shujiang Tu; Fang Fang; Songlei Zhu; Tuanjie Li; Xiaojing Zhang; Qiya Zhuang; Shuijun Ji; Yong Zhang

Publisher
Journal of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
73 KB
Volume
42
Category
Article
ISSN
0022-152X

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✦ Synopsis

The synthesis of bifunctional pyridine and quinolione derivatives were investigated using terephthalic and isophthalic aldehydes as a precursor. The reaction proceeds under microwave irradiation with good yield (70-92%) and short reaction time (7-9 min.). We provide a rapid and efficient method of synthesizing a range of bifunctional monocyclic and bicyclic products related to 1,4-dihydropyridines (1,4-DHPs).

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