## Abstract For Abstract see ChemInform Abstract in Full Text.
Microwave-Assisted Synthesis of Highly Substituted Aminomethylated 2-Pyridones
✍ Scribed by Pemberton, Nils; Åberg, Veronica; Almstedt, Hanna; Westermark, Andreas; Almqvist, Fredrik
- Book ID
- 117988409
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 159 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
A rapid and convenient synthesis of the 3-trifluoromethanesuifonyloxy-2-pyridone 2, one of the first examples of this class of compound, was achieved by Vilsmeier formylation and cyclisation of the acyl enamine 6. The triflate 2 was found to undergo a range of palladium-catalysed coupling reactions
## Abstract A series of pyridone derivatives were synthesized by the reaction of aromatic aldehydes, 1,3‐dicarbonyl compounds and ammonium acetate under microwave irradiation in the absence of solvent. The reactions were completed within __3‐__5 min to give the desired products in 72.4‐86.2% yields