Microwave-Assisted Synthesis of Biotin Conjugates with Quinolone Antibiotics via Amino Acids
β Scribed by Panda, Siva; Naumov, Roman; Asiri, Abdullah; Katritzky, Alan
- Book ID
- 121660887
- Publisher
- Thieme Medical Publishers
- Year
- 2014
- Tongue
- German
- Weight
- 209 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0039-7881
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## Abstract In this paper, we describe the thiolβene βclickβ reaction with modified poly methacrylic acid in water. The thiol group was implemented by a polymer analogous condensation reaction of polymethacrylic acid (**1**) and cysteamine (**2**), which was carried out in bulk by use of microwave.
A new method for synthesis of 3'-end-phosphorylated DNA oligomers via the phosphoramidite method with allyl protection has been developed. This method is particularly useful for the preparation of derivatives with base-labile structures such as oligoDNA-OPO(OH)OCH2CH(R)Z, in which Z is an electron-w