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Microwave-assisted synthesis of 2-amino and 2-azetidinonyl 5-(2-benzoyl-phenoxymethyl) 1,3,4-oxadiazoles

✍ Scribed by Shaukath Ara Khanum; S. Shashikanth; B. S. Sudha

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 93 KB
Volume: 15
Category: Article
ISSN: 1042-7163
DOI: 10.1002/hc.10210

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✦ Synopsis

Abstract

A simple high yielding method for the integration of heterocyclic rings viz. 1,3,4‐oxadiazole and azetidin‐2‐one at the benzophenone nucleus has been developed starting from substituted 2‐hydroxybenzophenones, and by using mild conditions, wet solid surface, and microwave irradiation. A comparison of this microwave‐accelerated reaction with conventional heating condition is also illustrated. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 15:37–42, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10210

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