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Microwave-Assisted Organocatalytic Enantioselective Intramolecular aza-Michael Reaction with α,β-Unsaturated Ketones

✍ Scribed by Prof. Dr. Santos Fustero ; Dr. Carlos del Pozo; Cristina Mulet; Rubén Lazaro; Dr. María Sánchez-Roselló


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
318 KB
Volume
17
Category
Article
ISSN
0947-6539

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Highly Enantio- and Diastereoselective O
✍ Juha Pulkkinen; Pompiliu S. Aburel; Nis Halland; Karl Anker Jørgensen 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 2 views

## Abstract A chiral imidazolidine catalyst was shown to catalyze the highly enantio‐ and diastereoselective domino Michael‐aldol reaction of β‐diketone and β‐ketosulfone derivatives with α,β‐unsaturated ketones to form optically active cyclohexanones having three or four contiguous chiral centers.