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Microwave-assisted multicomponent diastereoselective 1,3-dipolar cycloaddition of ethyl glyoxylate derived azomethine ylides

✍ Scribed by Mancebo-Aracil, Juan ;Nájera, Carmen ;Sansano, José M.


Book ID
118164614
Publisher
Royal Society of Chemistry
Year
2013
Tongue
English
Weight
436 KB
Volume
11
Category
Article
ISSN
1477-0520

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Diastereoselective synthesis of pyrrolid
✍ K. Karthikeyan; R. Senthil Kumar; D. Muralidharan; P.T. Perumal 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 691 KB

1,3-Dipolar cycloaddition of D-glucose-derived azomethine ylides for the synthesis of chiral pyrrolidines accompanied an unexpected 1,2-elimination in the furanose moiety of the products. The C3 0 alkoxy/ hydroxy group of the furanose moiety was invariably eliminated under the reaction conditions. A