Microwave activated solvent-free cascade reactions yielding highly functionalised 1,3-thiazines

✍ Scribed by Lal Dhar S. Yadav; Amrish Singh

• Book ID: 104253990
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 103 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)01353-4

✦ Synopsis

One-pot cascade reactions of N-acylglycines, acetic anhydride, anhydrous sodium acetate, aromatic aldehydes, and ammonium N-aryldithiocarbamates expeditiously and diastereoselectively yield 5-acylamino-3,6-diarylperhydro-2-thioxo-1,3-thiazin-4-ones (5a-j) in solvent-free conditions under microwave irradiation.