✦ LIBER ✦
Microvascular protective activity of flavonoid glucuronides fraction from Tulipa gesneriana
✍ Scribed by Jaromir Budzianowsk; Krystyna Korzeniowska; Ewa Chmara; Aleksander Mrozikiewicz
- Book ID
- 101290438
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 49 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
✦ Synopsis
A mixture of flavonoid glucuronides, consisting of 7-O-glucuronides of kaempferol and quercetin 3-Orutinosides, 3-O-gentiobiosides and 3-O-glucosides, was isolated from the perianths of Tulipa gesneriana L. var. 'Paradae'. It showed protective activity against the increased (both chloroform and histamine) skin vascular permeability in rabbits. The protective effect, measured as the reduction in leakage of Evans blue, was 59.8% after peritoneal treatment at a dose of 25 mg/kg, while that of troxerutin was 45.5%.