Desmopressin acetate decreases blood loss after cardiac surgery by activating platelets. We studied whether this effect was detrimental to small-caliber vein grafts in rats. Thirty minutes before femoral artery grafting with 0.75-mm-diameter reverse autogenous saphenous vein grafts, 20 rats received
Microvascular grafts: Effect of diameter discrepancy on patency rates
โ Scribed by Dr. Jose J. Monsivais
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 256 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0738-1085
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โฆ Synopsis
Abstract
This study examined the effects of diameter discrepancy between interpositional vein grafts within a range of 0.25 to 2 mm. One hundred rats underwent isolation of a 10 mm segment of the femoral artery, from which a 4 mm segment was removed. Venous grafts measuring 8 ยฑ 2 mm were interposed. The rats were categorized by their graft to artery diameter ratios. Patency was assessed upon completion and 4โ6 days postoperatively. All surgical specimens were submitted to the pathology department for microscopic evaluation. Results showed Group I: graft to artery ratio 1:1, patency rate 90% (18/20); Group II:ratio 0.75:1, patency rate 80% (16/20); Group III:ratio 0.5:1, patency rate 60% (12/20), Group IV: ratio 0.25:1, patency rate 20% (4/20); Group V:ratio 2:1, patency rate 60% (12/20). It is concluded that 1:1 venous graft to artery ratios are optimal. When this is impossible, diameter discrepancies should be at least 0.75:1 for acceptable patency rates to be attained in microvascular grafting.
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