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Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery

✍ Scribed by Agrawal, V K; Copeland, K M; Barbachano, Y; Rahim, A; Seth, R; White, C L; Hingorani, M; Nutting, C M; Kelly, M; Harris, P


Book ID
109855078
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
810 KB
Volume
16
Category
Article
ISSN
0969-7128

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Background Efficient gene transfer is a major challenge for non-viral gene therapy. Understanding how non-viral vectors initiate gene expression could lead to the development of new future vectors with enhanced efficacy. Methods Linear or branched polyethylenimine (PEI)/DNA complexes were generated