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Microtubule depolymerization facilitates contraction of vascular smooth muscle via increased activation of RhoA/Rho-kinase

✍ Scribed by K Chitaley; R.C Webb

Book ID
117840199
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
133 KB
Volume
56
Category
Article
ISSN
0306-9877

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## Abstract ## Aims To investigate the concentration and activity of RhoA in detrusor and urothelium, as well as the effects of a Rho‐kinase inhibitor, Y‐27632 {(+)‐(R)‐trans‐4‐(1‐aminoethyl)‐N‐(4‐pyridyl) cyclohexanecarboxamide dihydrochloride}, on contraction of the pig urinary bladder. ## Meth