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Microtubule Binding and Rotation of the Kinesin-14 Stalk

✍ Scribed by Endow, Sharyn A.; Liang, Zhang-Yi; Hallen, Mark A.


Book ID
123046423
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
39 KB
Volume
96
Category
Article
ISSN
0006-3495

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The kinesin-14, Ncd, is a cellular motor involved in microtubule spindle assembly and contraction during mitosis and meiosis. Like other members of the kinesin superfamily, Ncd consists of two motor heads connected by a linker and a long cargo-carrying stalk. The motor heads hydrolyze ATP to ADP to