Microtechnology for Cell Manipulation and Sorting

✍ Scribed by Wonhee Lee, Peter Tseng, Dino Di Carlo (eds.)

• Publisher: Springer International Publishing
• Year: 2017
• Tongue: English
• Leaves: 287
• Series: Microsystems and Nanosystems
• Edition: 1
• Category: Library

✦ Synopsis

This book delves into the recent developments in the microscale and microfluidic technologies that allow manipulation at the single and cell aggregate level. Expert authors review the dominant mechanisms that manipulate and sort biological structures, making this a state-of-the-art overview of conventional cell sorting techniques, the principles of microfluidics, and of microfluidic devices. All chapters highlight the benefits and drawbacks of each technique they discuss, which include magnetic, electrical, optical, acoustic, gravity/sedimentation, inertial, deformability, and aqueous two-phase systems as the dominant mechanisms utilized by microfluidic devices to handle biological samples. Each chapter explains the physics of the mechanism at work, and reviews common geometries and devices to help readers decide the type of style of device required for various applications. This book is appropriate for graduate-level biomedical engineering and analytical chemistry students, as well as engineers and scientists working in the biotechnology industry.

✦ Table of Contents

Front Matter....Pages i-ix
Microfluidic Cell Sorting and Separation Technology....Pages 1-14
Magnetic Cell Manipulation and Sorting....Pages 15-55
Electrical Manipulation and Sorting of Cells....Pages 57-92
Optical Manipulation of Cells....Pages 93-128
Acoustic Cell Manipulation....Pages 129-173
Gravity-Driven Fluid Pumping and Cell Manipulation....Pages 175-192
Inertial Microfluidic Cell Separation....Pages 193-223
Microfluidic Technologies for Deformability-Based Cell Sorting....Pages 225-254
Microfluidic Aqueous Two-Phase Systems....Pages 255-278
Back Matter....Pages 279-281

✦ Subjects

Nanotechnology and Microengineering;Biomedical Engineering;Biochemical Engineering;Biological and Medical Physics, Biophysics;Microengineering;Cell Biology