Microsphere studies of Bullfrog central vascular shunts during diving and breathing in air
✍ Scribed by Meyers, R. S. ;Moalli, R. ;Jackson, D. C. ;Millard, R. W.
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 335 KB
- Volume
- 208
- Category
- Article
- ISSN
- 0022-104X
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✦ Synopsis
Abstract
Bidirectional central vascular shunts were measured during diving and breathing in air in unanesthetized bullfrogs by using pulmonary trapping of 38μ mean diameter radionuclide‐labelled microspheres. Six animals studied during diving exhibited a strong overall right‐to‐left shunting pattern comprised of both a predominant (68% mean) right‐to‐left shunt and a weak (23%) left‐to‐right countershunt. Five animals with access to air showed a variety of distribution patterns, including predominant shunts in the left‐to‐right (1 animal) and right‐to‐left (1 animal) directions, nearly complete mixing (2 animals) and separation of systemic and pulmonary venous returns (1 animal).