Regulation of prostaglandin E2 synthase
✍
Antonio Carlos Pinheiro de Oliveira; Eduardo Candelario-Jalil; Harsharan S. Bhat
📂
Article
📅
2008
🏛
John Wiley and Sons
🌐
English
⚖ 575 KB
## Abstract Prostaglandin E~2~ (PGE~2~) is among the most important mediators involved in neuroinflammatory processes. The final step of its synthesis is regulated by enzymes termed prostaglandin E~2~ synthases (PGES). Three PGES are known, cytosolic (c)PGES, membrane‐associated (m)PGES‐1 and mPGES