ALPRAZOLAM HYDROXYLATION BY MOUSE LIVER
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KEVIN P. CHARPENTIER; LISA L. VON MOLTKE; JOSEPH W. POKU; JEROLD S. HARMATZ; RIC
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Article
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1997
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John Wiley and Sons
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English
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The eects of age on hepatic microsomal enzyme induction were studied in male CD-1 mice. Six week old and 1 year old animals were treated with either phenobarbital (80 mg kg 71 ) or saline once daily for 3 d. Twenty-four hours after the last treatment, animals were sacriยฎced and livers were harvested