Microsomal Cytochrome P450 Levels and Activities of Isolated Rat Livers Perfused with Albumin
β Scribed by Ragini Vuppugalla; Rakhi B. Shah; Anjaneya P. Chimalakonda; Charles W. Fisher; Reza Mehvar
- Book ID
- 110416140
- Publisher
- Springer US
- Year
- 2003
- Tongue
- English
- Weight
- 125 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0724-8741
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Assay conditions in determining total cytochrome P-450 in four laboratories were compared. Although the determination was derived from the original Omura and Sato method in each laboratory, the four standard protocols differed slightly, resulting in considerable differences in the results. Since the
The steady-state disposition of chlorzoxazone (CZX) and its hydroxylated metabolite 6-hydroxychlorzoxazone (HCZX) was determined in a single-pass isolated perfused rat liver (IPRL) model using constant CZX concentrations of 10-200 microM. The concentrations of CZX, HCZX, and/or HCZX glucuronide in t