✦ LIBER ✦
Microscale Electrolytic Fluorinations of 4-Nitrotoluene - Cell Construction, Computer Monitor and Control, and Chemistry
✍ Scribed by S.C. Savett; S.M. Lee; A.Z. Bradley; S.P. Kneizys; J.M. Lobue; W.J. Middleton
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 392 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0026-265X
No coin nor oath required. For personal study only.
✦ Synopsis
An electrochemical microcell that can utilize a 70:30 mixture of (\mathrm{HF}) and pyridine as both the solvent and the supporting electrolyte was constructed and interfaced with a computer for monitoring and control. 4-Nitrotoluene was selectively fluorinated in the cell in good yield and good conversion to give an 83:17 mixture of two monofluoro products, (\alpha)-fluoro4-nitrotoluene and 2-fluoro-5-nitrotoluene (a product of rearrangement). C 1993 Academic Press. Inc.