Microsatellite typing identifies the major clades of the human pathogen Candida albicans
✍ Scribed by Julio Chávez-Galarza; Célia Pais; Paula Sampaio
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 312 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1567-1348
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This study examines the macrogeographic population structure of Candida albicans, a yeast commensal of humans, through a population genetic analysis of 5 microsatellite loci in 13 cities. The populations were predominantly clonal with some recombination. About 5% of the genetic variation is between
## Abstract Virulence of __C. albicans__ strains can be tested using a mouse model of haematogenously disseminated __Candida__ cells. Initial steps of host‐pathogen contact such as adhesion and colonization are not taken into account due to the injection of __Candida__ cells into the blood stream.