Microsatellite instability influences histology and prognosis in mucinous carcinoma of the colorectum
β Scribed by Kakar, Sanjay N/a; Burgart, Lawrence J.; Thobodeau, Stephen; Smyrk, Thomas C.
- Book ID
- 124104177
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 185 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0016-5085
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π SIMILAR VOLUMES
Fifty sporadic colorectal carcinomas diagnosed in 1991 were analysed for microsatellite instability at four loci. Five of 50 (10 per cent) tumours showed replication errors (RERs) at two or more loci and were classed as RER-positive (RER+). A further five showed RERs at one locus only. A significant
## Abstract Intraductal papillaryβmucinous carcinoma (IPMC) of the pancreas, a new entity of pancreatic cancer with a favorable prognosis, has shown a gradual increase in the number of reported cases. Patients with highβfrequency microsatellite instability (MSIβH) tumors have been shown to survive