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Microsatellite instability indicates better prognosis in colorectal cancer

✍ Scribed by Kathryn Senior

Book ID
117292139
Publisher
The Lancet
Year
2000
Tongue
English
Weight
50 KB
Volume
355
Category
Article
ISSN
0140-6736

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Fifty sporadic colorectal carcinomas diagnosed in 1991 were analysed for microsatellite instability at four loci. Five of 50 (10 per cent) tumours showed replication errors (RERs) at two or more loci and were classed as RER-positive (RER+). A further five showed RERs at one locus only. A significant