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MicroRNAs: Key Modulators of Posttranscriptional Gene Expression

โœ Scribed by Steven P. O'Hara; Justin L. Mott; Patrick L. Splinter; Gregory J. Gores; Nicholas F. LaRusso

Book ID
119760724
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
774 KB
Volume
136
Category
Article
ISSN
0016-5085

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Thymidylate synthase (TS) is an essential enzyme that catalyzes the formation of thymidylic acid in the de novo biosynthetic pathway and i s the target enzyme for a variety of chemotherapeutic agents. The TS gene is expressed at a much higher level in proliferating cells than in quiescent cells. Con