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MicroRNAs in the pathogenesis of neuroblastoma

✍ Scribed by Johannes H. Schulte; Sebastian Horn; Stefanie Schlierf; Alexander Schramm; Lukas C. Heukamp; Holger Christiansen; Reinhard Buettner; Bernd Berwanger; Angelika Eggert

Book ID
116334884
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
195 KB
Volume
274
Category
Article
ISSN
0304-3835

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## Abstract __MYCN__ amplification is a common feature of aggressive tumour biology in neuroblastoma. The MYCN transcription factor has been demonstrated to induce or repress expression of numerous genes. MicroRNAs (miRNA) are a recently discovered class of short RNAs that repress translation and p