MicroRNAs as biomarkers of disease onset
β Scribed by Maciej Ciesla; Klaudia Skrzypek; Magdalena Kozakowska; Agnieszka Loboda; Alicja Jozkowicz; Jozef Dulak
- Book ID
- 105894391
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 277 KB
- Volume
- 401
- Category
- Article
- ISSN
- 1618-2650
No coin nor oath required. For personal study only.
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We consider the analysis of serial biomarkers to screen and monitor individuals in a given population for onset of a speci"c disease of interest. The biomarker readings are subject to error. We survey some of the existing literature and concentrate on two recently proposed models. The "rst is a full
Mature microRNAs (miRNAs) are evolutionarily conserved small noncoding RNAs that are initially transcribed as primary transcripts [primary microRNAs (pri-miRNAs)]. 1 miRNAs have been identified in a wide range of species, and approximately 1400 are found in humans. It has been estimated that more th