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MicroRNAs and their roles in aging

✍ Scribed by Smith-Vikos, T.; Slack, F. J.

Book ID: 121273947
Publisher: The Company of Biologists Ltd
Year: 2012
Tongue: English
Weight: 635 KB
Volume: 125
Category: Article
ISSN: 0021-9533
DOI: 10.1242/jcs.099200

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## Abstract microRNAs (miRNAs) are an abundant class of newly identified endogenous non‐protein‐coding small RNAs. They exist in animals, plants, and viruses, and play an important role in gene silencing. Translational repression, mRNA cleavage, and mRNA decay initiated by miRNA‐directed deadenylat