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MicroRNAs and micromanaging the skeleton in disease, development and evolution

✍ Scribed by Xinjun He; Johann K. Eberhart; John H. Postlethwait

Book ID
114778601
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2009
Tongue
English
Weight
836 KB
Volume
13
Category
Article
ISSN
1582-1838

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## Abstract How might changes in developmental regulatory pathways underlie evolutionary changes in morphology? Here we focus on a particular pathway regulated by a secreted, signaling peptide, Endothelin1 (Edn1). Developmental genetic analyses show the Edn1‐pathway to be crucial for hyomandibular