MicroRNA expression profiling in blood from fragile X-associated tremor/ataxia syndrome patients
✍ Scribed by Alvarez-Mora, M. I.; Rodriguez-Revenga, L.; Madrigal, I.; Torres-Silva, F.; Mateu-Huertas, E.; Lizano, E.; Friedländer, M. R.; Martí, E.; Estivill, X.; Milà, M.
- Book ID
- 120561676
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 477 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1601-1848
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## Abstract Fragile X–associated tremor/ataxia syndrome (FXTAS) is a progressive adult‐onset tremor/ataxia syndrome caused by premutations in the __FMR1__ gene. In cranial MRI, the most characteristic findings are bilateral T2 hyperintense lesions within the middle cerebellar peduncles. Here we pre
## Abstract There is no established treatment for the neurological features of the recently discovered fragile X–associated tremor/ataxia syndrome (FXTAS). Fifty‐six patients with FXTAS completed a questionnaire to determine whether any medications had been effective for neurological symptoms. Of 1