Unsaturated fatty acids inhibit the expr
✍
Manlio Vinciguerra; Antonino Sgroi; Christelle Veyrat-Durebex; Laura Rubbia-Bran
📂
Article
📅
2008
🏛
John Wiley and Sons
🌐
English
⚖ 736 KB
Phosphatase and tensin homolog (PTEN) is a regulator of phosphoinositide 3-kinase signaling and an important tumor suppressor mutated/deleted in human cancers. PTEN deletion in the liver leads to insulin resistance, steatosis, inflammation, and cancer. We recently demonstrated that unsaturated fatty