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โฆ Synopsis
This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. Chapters contributed by leading scientists examine recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness. The authors contextualize microRNAs within epigenetics and micropeptidomics, angiongenesis and atherosclerosis, endometrial pathophysiology, and more. Throughout, numerous color photographs, diagrams of molecular pathways, and tables enhance the text.
microRNA: Basic Science is an ideal companion to both microRNA: Medical Evidenceand microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.
โฆ Table of Contents
Front Matter....Pages i-xiii A Fleeting Glimpse Inside microRNA, Epigenetics, and Micropeptidomics....Pages 1-14 The microRNA Machinery....Pages 15-30 microRNAs in Mitochondria: An Unexplored Niche....Pages 31-51 microRNAs Distinctively Regulate Vascular Smooth Muscle and Endothelial Cells: Functional Implications in Angiogenesis, Atherosclerosis, and In-Stent Restenosis....Pages 53-77 Mechanistic Role of MicroRNAs in Coupling Lipid Metabolism and Atherosclerosis....Pages 79-100 microRNAs in Pancreatic ฮฒ-Cell Physiology....Pages 101-117 microRNA and Cardiac Regeneration....Pages 119-141 microRNAs and Endometrial Pathophysiology....Pages 143-155 microRNA and NF-kappa B....Pages 157-170 microRNAs: Key Players in Hematopoiesis....Pages 171-211 Regulatory Roles of miRNAs in Aging....Pages 213-230 Computational Prediction of microRNA Targets....Pages 231-252 Back Matter....Pages 253-257
โฆ Subjects
Cell Physiology; Atomic/Molecular Structure and Spectra; Animal Biochemistry; Molecular Medicine; Human Physiology
โ Gaetano Santulli (eds.)๐ Library๐ 2015๐ Springer International Publishing๐ English
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โ Gaetano Santulli (eds.)๐ Library๐ 2015๐ Springer International Publishing๐ English
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โ Beverley J. Hunt, Lucilla Poston, Michael Schachter, Alison W. Halliday๐ Library๐ 2002๐ English
This updated and expanded new edition takes full account of recent developments and conveys the basic science underlying a wide range of clinical conditions including atherosclerosis, hypertension, diabetes, and pregnancy. As with the first edition, the publication provides an introductory account o
โ Beverley J. Hunt, Lucilla Poston, Michael Schachter, Alison W. Halliday๐ Library๐ 2002๐ Cambridge University Press๐ English
This updated and expanded new edition takes full account of recent developments and conveys the basic science underlying a wide range of clinical conditions including atherosclerosis, hypertension, diabetes, and pregnancy. As with the first edition, the publication provides an introductory account o