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MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor

✍ Scribed by Waaijer, Mariëtte E. C.; Wieser, Matthias; Grillari-Voglauer, Regina; Heemst, Diana; Grillari, Johannes; Maier, Andrea B.

Book ID: 121698470
Publisher: Springer
Year: 2014
Tongue: English
Weight: 254 KB
Volume: 15
Category: Article
ISSN: 1389-5729
DOI: 10.1007/s10522-014-9496-1

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Objectives: Reactive oxygen species account for the background levels of oxidatively damaged DNA in normal tissues. Physical exercise increases oxygen consumption and can cause oxidative stress. This stress can also involve deficient antioxidant defenses, which can be influenced by certain genetic p