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MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms

โœ Scribed by Wang, Y.; Toh, H. C.; Chow, P.; Chung, A. Y. F.; Meyers, D. J.; Cole, P. A.; Ooi, L. L. P. J.; Lee, C. G. L.


Book ID
111958738
Publisher
The Federation of American Societies for Experimental Biology
Year
2012
Tongue
English
Weight
459 KB
Volume
26
Category
Article
ISSN
0892-6638

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Loss of heterozygosity (LOH) at 1p36 occurs in a number of solid tumors including hepatocellular carcinoma (HCC). Recently, a novel gene, p73, has been identified at 1p36.33. p73 is structurally and functionally related to p53 located at 17p13.1, which is a target for inactivation in HCCs. p73 produ