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microRNA-21 is upregulated in malignant melanoma and influences apoptosis of melanocytic cells

โœ Scribed by Imke Satzger; Anika Mattern; Uta Kuettler; Dirk Weinspach; Margarete Niebuhr; Alexander Kapp; Ralf Gutzmer


Book ID
114795887
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
320 KB
Volume
21
Category
Article
ISSN
0906-6705

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## Abstract MicroRNAs (miRNAs) are small noncoding RNAs (โˆผ22 bp) that posttranscriptionally regulate gene expression. MiRNAs possess oncogenic or tumor suppressor activity in various tumors but little is known about miRNA expression pattern in malignant melanoma. We determined the expression level