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MicroRNA-143 as a tumor suppressor in liposarcoma

✍ Scribed by Stacy Ugras; Penelope DeCarolis; Aimee Crago; Ryan M. Gobble; Christina Angeles; Elliott Brill; Raya Khanin; Nicholas Socci; Thomas Tuschl; Samuel Singer

Book ID
113680145
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
91 KB
Volume
211
Category
Article
ISSN
1072-7515

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The study from Dr. Sun's group explained an interesting phenomenon on why microRNA-143, a commonly down-regulated mi-croRNA in many types of cancer, expressed at a high level in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). They used a hepatitis B virus x protein (HBx) transgenic m