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microRNA-1274a, a modulator of sorafenib induced a disintegrin and metalloproteinase 9 (ADAM9) down-regulation in hepatocellular carcinoma

✍ Scribed by Changchun Zhou; Jibing Liu; Yang Li; Li Liu; Xiaojiao Zhang; Cheng-yuan Ma; Shu-cheng Hua; Ming Yang; Qipeng Yuan


Book ID
113622539
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
728 KB
Volume
585
Category
Article
ISSN
0014-5793

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Sorafenib inhibits the shedding of major
✍ Keisuke Kohga; Tetsuo Takehara; Tomohide Tatsumi; Hisashi Ishida; Takuya Miyagi; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 815 KB

The ectodomain of major histocompatibility complex class I-related chain A (MICA) is shed from tumor cells, and may be an important means of evading antitumor immunity. This study investigated the roles of a disintegrin and metalloproteinase 9 (ADAM9) in the shedding of MICA in human hepatocellular