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Micropreparative focusing of proteins in carrier-ampholyte-free solution with electrically controlled compositions of electrolytes

✍ Scribed by Jan Pospíchal; Josef Chmelík; Mirko Deml


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
457 KB
Volume
7
Category
Article
ISSN
1040-7685

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✦ Synopsis


Three proteins (myoglobin, ribonuclease, and cytochrome C) were concentrated, separated, and isolated from a dilute mixture by electrically controlled focusing in carrier-ampholyte-free solution. Electrolytes were modified at both sides of the capillary. The described method is suitable for the micropreparation of hundred-pg quantities of proteins in times comparable to other capillary techniques (tens of minutes).