## Abstract Targeting specific sites in vivo for the delivery of therapeutic compounds presents a major obstacle to the treatment of many diseases. One targeted delivery technique that has gained prominence in recent years is the use of magnetic nanoparticles. In these systems, therapeutic compound
Microparticles and nanoparticles for drug delivery
β Scribed by Daniel S. Kohane
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 248 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0006-3592
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β¦ Synopsis
Abstract
Particulate drug delivery systems have become important in experimental pharmaceutics and clinical medicine. The distinction is often made between microβ and nanoparticles, being particles with dimensions best described in micrometers and nanometers respectively. That size difference entails real differences at many levels, from formulation to in vivo usage. Here I will discuss those differences and provide examples of applications, for local and systemic drug delivery. I will outline a number of challenges of interest in particulate drug delivery. Biotechnol. Bioeng. 2007;96: 203β209. Β© 2006 Wiley Periodicals, Inc.
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