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Micronuclei induced by modulators of methylation: Analogs of 5-azacytidine

✍ Scribed by Carsten Körber; Petra Gibis; Diane L. Spencer; William J. Caspary; H. Stopper


Book ID
114133276
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
169 KB
Volume
360
Category
Article
ISSN
0165-1161

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The 5-ACR (5-azacytidine) introduced in human lymphocyte cultures induces a lack or a delay of condensation of some chromosome segments corresponding to the G-bands. The resulting R-banding is very similar to that obtained with a 7-h treatment by BrdU, although the segmentation may be much stronger