Paradoxical anticonvulsant acitivity of
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Lechoslaw Turski; Stefan Diedrichs; Thomas Klockgether; Michael Schwarz; Waldema
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Article
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1991
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John Wiley and Sons
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English
⚖ 797 KB
Bicuculline methiodide (BMI), a y-aminobutyrate (GABA) antagonist, is a powerful convulsant agent when injected into the cerebral ventricles, amygdala, hippocampus, thalamus, neocortex, and deep prepiriform cortex in rats. In contrast, bilateral microinjection of BMI into the rat striatum confers pr