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Microinjection of dynorphin into the hippocampus impairs spatial learning in rats

✍ Scribed by Katherine L. McDaniel; William R. Mundy; Hugh A. Tilson

Book ID
113223790
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
695 KB
Volume
35
Category
Article
ISSN
0091-3057

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The effects of aging on extracellular glutamate and tissue dynorphin content in the hippocampus were examined in Fischer-344 rats. Young adult (4-month-old) and aged (24-month-old) rats were trained to find a hidden platform in the Morris water task. Aged rats were unable to acquire the spatial lear