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Microinjection of an Antibody to the Ku Protein Arrests Development in Sea Urchin Embryos

โœ Scribed by Jyotshna Kanungo, Ruth M. Empson and Howard Rasmussen


Book ID
125735315
Publisher
Marine Biological Laboratory
Year
1999
Tongue
English
Weight
889 KB
Volume
197
Category
Article
ISSN
0006-3185

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Microinjection of an antibody against th
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## Abstract We reported recently that the inhibition of cysteineโ€proteases with Eโ€64โ€d disturbs DNA replication and prevents mitosis of the early sea urchin embryo. Since Eโ€64โ€d is a rather general inhibitor of thiolโ€proteases, to specifically target the cysteineโ€protease previously identified in o