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Microglial zinc uptake via zinc transporters induces ATP release and the activation of microglia

โœ Scribed by Youichirou Higashi; Shohei Segawa; Takaaki Matsuo; Shogo Nakamura; Yukiko Kikkawa; Kentaro Nishida; Kazuki Nagasawa


Book ID
118283704
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
769 KB
Volume
59
Category
Article
ISSN
0894-1491

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## Abstract Trimethyltin (TMT) is a neurotoxicant known to induce early microglial activation. The present study was undertaken to investigate the role played by these microglial cells in the TMTโ€induced neurotoxicity. The effects of TMT were investigated in monolayer cultures of isolated microglia