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Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E

โœ Scribed by Barger, Steven W.; Harmon, Ashley D.


Book ID
109805083
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
415 KB
Volume
388
Category
Article
ISSN
0028-0836

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## Abstract Apolipoprotein E4 (apoE4) genotype is associated with an increased risk for Alzheimer's disease (AD). This is thought to be in part attributable to an impact of apoE genotype on the processing of the transmembrane amyloid precursor protein (APP) thereby contributing to amyloid beta pept