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Microglia: Proliferation and activation driven by the P2X7 receptor

✍ Scribed by Mastura Monif; Geoffrey Burnstock; David A. Williams


Book ID
116307954
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
423 KB
Volume
42
Category
Article
ISSN
1357-2725

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## Abstract The peroxisome proliferator‐activated receptor‐α (PPAR‐α) plays a key role in lipid metabolism and inflammation. Recently, we demonstrated that administration of the PPAR‐α agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE